Stephen P. Coburn, "Mathematical Modeling in Experimental Nutrition: Vitamins, Proteins, Methods, Volume 40 (Advances in Food and Nutrition Research)" 1 edition | English | 1996-10-16 | ISBN: 012016440X | 385 pages | PDF | 16,4 mb This book developed from a series of conferences to facilitate the application of mathematical modeling to experimental nutrition. As nutrition
science moves from prevention of gross deficiencies to identifying
requirements for optimum long term health, more sophisticated methods of nutritional assessment will be needed. Collection and evaluation of kinetic data may be one such method.This books opens with chapters giving specific examples of the application of modeling techniques
to vitamin A, carotenoids, folate, vitamin b-6, glycogen phosphorylase,
transthyretin, amino acids, and energy metabolism. Obtaining kinetic
data on internal processes is a major challenge; therefore, the text
includes chapters on the use of microdialysis and ultrafiltration, use
of membrane vesicles, and culture of mammary tissue. Many of the authors
use the Simulation, Analysis and Modeling program which allows
compartmental models to be described without specifying the required
differential equations. The final sections of the book, however, present
some more mathematical descriptions of physiological processes,
including bioperiodicity, metabolic control, and membrane transport;
discussions of some computational aspects of modeling such as parameter
distributions, linear integrators and identifiability; and alternative
mathematical approaches such as neural networks and graph theory.
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